From Technology Review
By adapting a programmable device used to manufacture integrated circuits, researchers have devised a semi-automated process to build polymer scaffolds for guiding the development of three-dimensional heart tissue. The method, which entails layer-by-layer fabrication, will enable more precise investigation of the three-dimensional cues that drive cells to organize and form tissue – and could serve as a platform for the development of implantable organ tissue. Tissue engineers can already make three-dimensional constructs of relatively simple tissues. But highly ordered cellular architectures essential to the function of complicated organs like the heart are much harder to replicate.